Lymphoscintigraphic evidence of lymph vessel dilation in the limbs of children with Brugia malayi infection.
Identifieur interne : 006A35 ( Main/Exploration ); précédent : 006A34; suivant : 006A36Lymphoscintigraphic evidence of lymph vessel dilation in the limbs of children with Brugia malayi infection.
Auteurs : R K Shenoy [Inde] ; T K Suma ; V. Kumaraswami ; G. Dhananjayan ; N. Rahmah ; G. Abhilash ; C. RameshSource :
- The Journal of communicable diseases [ 0019-5138 ] ; 2008.
Descripteurs français
- KwdFr :
- Adolescent, Animaux, Brugia malayi (isolement et purification), Brugia malayi (pathogénicité), Dilatation pathologique (imagerie diagnostique), Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique (imagerie diagnostique), Filariose lymphatique (parasitologie), Filariose lymphatique (physiopathologie), Humains, Inde, Malformations lymphatiques (imagerie diagnostique), Malformations lymphatiques (parasitologie), Malformations lymphatiques (physiopathologie), Membres (), Membres (imagerie diagnostique), Mâle, Noeuds lymphatiques (imagerie diagnostique), Noeuds lymphatiques (parasitologie), Noeuds lymphatiques (physiopathologie), Scintigraphie ().
- MESH :
- imagerie diagnostique : Dilatation pathologique, Filariose lymphatique, Malformations lymphatiques, Membres, Noeuds lymphatiques.
- isolement et purification : Brugia malayi.
- parasitologie : Filariose lymphatique, Malformations lymphatiques, Noeuds lymphatiques.
- pathogénicité : Brugia malayi.
- physiopathologie : Filariose lymphatique, Malformations lymphatiques, Noeuds lymphatiques.
- Adolescent, Animaux, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Inde, Membres, Mâle, Scintigraphie.
English descriptors
- KwdEn :
- Adolescent, Animals, Brugia malayi (isolation & purification), Brugia malayi (pathogenicity), Child, Child, Preschool, Dilatation, Pathologic (diagnostic imaging), Elephantiasis, Filarial (diagnostic imaging), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (physiopathology), Extremities (blood supply), Extremities (diagnostic imaging), Female, Humans, India, Lymph Nodes (diagnostic imaging), Lymph Nodes (parasitology), Lymph Nodes (physiopathology), Lymphatic Abnormalities (diagnostic imaging), Lymphatic Abnormalities (parasitology), Lymphatic Abnormalities (physiopathology), Male, Radionuclide Imaging (methods).
- MESH :
- blood supply : Extremities.
- diagnostic imaging : Dilatation, Pathologic, Elephantiasis, Filarial, Extremities, Lymph Nodes, Lymphatic Abnormalities.
- isolation & purification : Brugia malayi.
- methods : Radionuclide Imaging.
- parasitology : Elephantiasis, Filarial, Lymph Nodes, Lymphatic Abnormalities.
- pathogenicity : Brugia malayi.
- physiopathology : Elephantiasis, Filarial, Lymph Nodes, Lymphatic Abnormalities.
- Adolescent, Animals, Child, Child, Preschool, Female, Humans, India, Male.
Abstract
Lymphatic filariasis (LF) is targeted for global elimination by the year 2020. It was earlier believed that LF is mostly a disease of adults. Recent studies indicate that in endemic countries filarial infection starts mostly in childhood even though the disease manifestations occur much later in life. The initial damage to the lymph vessels where the adult worms are lodged is dilation, thought to be irreversible even with treatment. Most of these studies relate to bancroftian filariasis. Studies that address this early pathology in brugian filariasis in humans are scarce. We report here for the first time, the lymphatic abnormalities seen on lymphoscintigraphy (LSG) in children with Brugia malayi filariasis. LSG was performed in 100 children aged between 3-15 years, who were enrolled in the study either because they were microfilaremic; had present or past filarial disease or were positive for antifilarial IgG4 antibodies. Inguinal and axillary lymph nodes were imaged in most children. Dilated lymph vessels were visualized in 80 children and this pathology was evenly distributed in all the three study groups. Lymph vessels dilation was seen even in three year old children. The implications of these findings for management of LF and control programmes are discussed.
PubMed: 19301693
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002F29
- to stream PubMed, to step Curation: 002F29
- to stream PubMed, to step Checkpoint: 002F29
- to stream Ncbi, to step Merge: 003304
- to stream Ncbi, to step Curation: 003304
- to stream Ncbi, to step Checkpoint: 003304
- to stream Main, to step Merge: 006B36
- to stream Main, to step Curation: 006A35
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymphoscintigraphic evidence of lymph vessel dilation in the limbs of children with Brugia malayi infection.</title><author><name sortKey="Shenoy, R K" sort="Shenoy, R K" uniqKey="Shenoy R" first="R K" last="Shenoy">R K Shenoy</name><affiliation wicri:level="1"><nlm:affiliation>Filariasis Chemotherapy Unit, T.D. Medical College Hospital, Alappuzha 688 011, Kerala, India. drrkshenoy@gmail.com</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Filariasis Chemotherapy Unit, T.D. Medical College Hospital, Alappuzha 688 011, Kerala</wicri:regionArea><wicri:noRegion>Kerala</wicri:noRegion></affiliation></author><author><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></author><author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name></author><author><name sortKey="Dhananjayan, G" sort="Dhananjayan, G" uniqKey="Dhananjayan G" first="G" last="Dhananjayan">G. Dhananjayan</name></author><author><name sortKey="Rahmah, N" sort="Rahmah, N" uniqKey="Rahmah N" first="N" last="Rahmah">N. Rahmah</name></author><author><name sortKey="Abhilash, G" sort="Abhilash, G" uniqKey="Abhilash G" first="G" last="Abhilash">G. Abhilash</name></author><author><name sortKey="Ramesh, C" sort="Ramesh, C" uniqKey="Ramesh C" first="C" last="Ramesh">C. Ramesh</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2008">2008</date><idno type="RBID">pubmed:19301693</idno><idno type="pmid">19301693</idno><idno type="wicri:Area/PubMed/Corpus">002F29</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002F29</idno><idno type="wicri:Area/PubMed/Curation">002F29</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002F29</idno><idno type="wicri:Area/PubMed/Checkpoint">002F29</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002F29</idno><idno type="wicri:Area/Ncbi/Merge">003304</idno><idno type="wicri:Area/Ncbi/Curation">003304</idno><idno type="wicri:Area/Ncbi/Checkpoint">003304</idno><idno type="wicri:doubleKey">0019-5138:2008:Shenoy R:lymphoscintigraphic:evidence:of</idno><idno type="wicri:Area/Main/Merge">006B36</idno><idno type="wicri:Area/Main/Curation">006A35</idno><idno type="wicri:Area/Main/Exploration">006A35</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Lymphoscintigraphic evidence of lymph vessel dilation in the limbs of children with Brugia malayi infection.</title><author><name sortKey="Shenoy, R K" sort="Shenoy, R K" uniqKey="Shenoy R" first="R K" last="Shenoy">R K Shenoy</name><affiliation wicri:level="1"><nlm:affiliation>Filariasis Chemotherapy Unit, T.D. Medical College Hospital, Alappuzha 688 011, Kerala, India. drrkshenoy@gmail.com</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Filariasis Chemotherapy Unit, T.D. Medical College Hospital, Alappuzha 688 011, Kerala</wicri:regionArea><wicri:noRegion>Kerala</wicri:noRegion></affiliation></author><author><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></author><author><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name></author><author><name sortKey="Dhananjayan, G" sort="Dhananjayan, G" uniqKey="Dhananjayan G" first="G" last="Dhananjayan">G. Dhananjayan</name></author><author><name sortKey="Rahmah, N" sort="Rahmah, N" uniqKey="Rahmah N" first="N" last="Rahmah">N. Rahmah</name></author><author><name sortKey="Abhilash, G" sort="Abhilash, G" uniqKey="Abhilash G" first="G" last="Abhilash">G. Abhilash</name></author><author><name sortKey="Ramesh, C" sort="Ramesh, C" uniqKey="Ramesh C" first="C" last="Ramesh">C. Ramesh</name></author></analytic><series><title level="j">The Journal of communicable diseases</title><idno type="ISSN">0019-5138</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Animals</term><term>Brugia malayi (isolation & purification)</term><term>Brugia malayi (pathogenicity)</term><term>Child</term><term>Child, Preschool</term><term>Dilatation, Pathologic (diagnostic imaging)</term><term>Elephantiasis, Filarial (diagnostic imaging)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Elephantiasis, Filarial (physiopathology)</term><term>Extremities (blood supply)</term><term>Extremities (diagnostic imaging)</term><term>Female</term><term>Humans</term><term>India</term><term>Lymph Nodes (diagnostic imaging)</term><term>Lymph Nodes (parasitology)</term><term>Lymph Nodes (physiopathology)</term><term>Lymphatic Abnormalities (diagnostic imaging)</term><term>Lymphatic Abnormalities (parasitology)</term><term>Lymphatic Abnormalities (physiopathology)</term><term>Male</term><term>Radionuclide Imaging (methods)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Animaux</term><term>Brugia malayi (isolement et purification)</term><term>Brugia malayi (pathogénicité)</term><term>Dilatation pathologique (imagerie diagnostique)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Filariose lymphatique (imagerie diagnostique)</term><term>Filariose lymphatique (parasitologie)</term><term>Filariose lymphatique (physiopathologie)</term><term>Humains</term><term>Inde</term><term>Malformations lymphatiques (imagerie diagnostique)</term><term>Malformations lymphatiques (parasitologie)</term><term>Malformations lymphatiques (physiopathologie)</term><term>Membres ()</term><term>Membres (imagerie diagnostique)</term><term>Mâle</term><term>Noeuds lymphatiques (imagerie diagnostique)</term><term>Noeuds lymphatiques (parasitologie)</term><term>Noeuds lymphatiques (physiopathologie)</term><term>Scintigraphie ()</term></keywords><keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Extremities</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Dilatation, Pathologic</term><term>Elephantiasis, Filarial</term><term>Extremities</term><term>Lymph Nodes</term><term>Lymphatic Abnormalities</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Dilatation pathologique</term><term>Filariose lymphatique</term><term>Malformations lymphatiques</term><term>Membres</term><term>Noeuds lymphatiques</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Brugia malayi</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Brugia malayi</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Radionuclide Imaging</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Malformations lymphatiques</term><term>Noeuds lymphatiques</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Lymph Nodes</term><term>Lymphatic Abnormalities</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Brugia malayi</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Brugia malayi</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Malformations lymphatiques</term><term>Noeuds lymphatiques</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Lymph Nodes</term><term>Lymphatic Abnormalities</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Animals</term><term>Child</term><term>Child, Preschool</term><term>Female</term><term>Humans</term><term>India</term><term>Male</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Animaux</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Inde</term><term>Membres</term><term>Mâle</term><term>Scintigraphie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphatic filariasis (LF) is targeted for global elimination by the year 2020. It was earlier believed that LF is mostly a disease of adults. Recent studies indicate that in endemic countries filarial infection starts mostly in childhood even though the disease manifestations occur much later in life. The initial damage to the lymph vessels where the adult worms are lodged is dilation, thought to be irreversible even with treatment. Most of these studies relate to bancroftian filariasis. Studies that address this early pathology in brugian filariasis in humans are scarce. We report here for the first time, the lymphatic abnormalities seen on lymphoscintigraphy (LSG) in children with Brugia malayi filariasis. LSG was performed in 100 children aged between 3-15 years, who were enrolled in the study either because they were microfilaremic; had present or past filarial disease or were positive for antifilarial IgG4 antibodies. Inguinal and axillary lymph nodes were imaged in most children. Dilated lymph vessels were visualized in 80 children and this pathology was evenly distributed in all the three study groups. Lymph vessels dilation was seen even in three year old children. The implications of these findings for management of LF and control programmes are discussed.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Abhilash, G" sort="Abhilash, G" uniqKey="Abhilash G" first="G" last="Abhilash">G. Abhilash</name><name sortKey="Dhananjayan, G" sort="Dhananjayan, G" uniqKey="Dhananjayan G" first="G" last="Dhananjayan">G. Dhananjayan</name><name sortKey="Kumaraswami, V" sort="Kumaraswami, V" uniqKey="Kumaraswami V" first="V" last="Kumaraswami">V. Kumaraswami</name><name sortKey="Rahmah, N" sort="Rahmah, N" uniqKey="Rahmah N" first="N" last="Rahmah">N. Rahmah</name><name sortKey="Ramesh, C" sort="Ramesh, C" uniqKey="Ramesh C" first="C" last="Ramesh">C. Ramesh</name><name sortKey="Suma, T K" sort="Suma, T K" uniqKey="Suma T" first="T K" last="Suma">T K Suma</name></noCountry><country name="Inde"><noRegion><name sortKey="Shenoy, R K" sort="Shenoy, R K" uniqKey="Shenoy R" first="R K" last="Shenoy">R K Shenoy</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006A35 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006A35 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:19301693
|texte= Lymphoscintigraphic evidence of lymph vessel dilation in the limbs of children with Brugia malayi infection.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:19301693" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |